StemoniX's microBrain® to be Featured in Podium Presentatio
MAPLE GROVE, Minn., Jan. 27, 2020 /PRNewswire/ -- StemoniX, a biotech company revolutionizing how new medicines are discovered, announced today that its Director of Applications, Oivin Guichert, Ph.D., will deliver a podium presentation highlighting the company's microBrain technology at the SLAS (Society for Laboratory Automation and Screening) 2020 International Conference & Exhibition at the San Diego Convention Center, Jan. 27-29, 2020. The presentation will be featured as part of the Assay Development and Screening Session during the annual meeting.
During the podium presentation, entitled "New innovation to solve unmet needs: Implementing human induced pluripotent stem cell-derived neural spheroids as a robust screening platform for phenotypic-based central nervous system drug discovery," Dr. Guichert will detail how performing a high-throughput functional screening assay on StemoniX's human induced pluripotent stem cell (iPSC)-derived 3D neural spheroid platform demonstrated the ability to identify a wide range of hits spanning multiple target areas. He will highlight how this model could provide relevant human platforms for disease-specific drug discovery to help overcome traditional hurdles of CNS-targeted drug discovery and development efforts.
Ping Yeh, co-founder and CEO of StemoniX, said: "The SLAS 2020 International Conference & Exhibition is an ideal event to showcase the value potential of our microOrgan platform and AnalytiX data management and analytical software. As presented by Dr. Guichert and in the six posters, microBrain, microHeart, microPancreas and AnalytiX offer the potential to reshape how drugs are discovered and developed by providing the opportunity to go from model to molecule to validated drug in a fraction of the time and cost required with traditional methods. This includes the near-term potential to identify and advance novel therapeutic targets for Rett syndrome by leveraging our groundbreaking in vitro microBrain model in partnership with AI drug discovery pioneer, Atomwise."
Podium Presentation Details
New innovation to solve unmet needs: Implementing human induced pluripotent stem cell-derived neural spheroids as a robust screening platform for phenotypic-based central nervous system drug discovery
Assay Development and Screening
SLAS 2020 International Conference & Exhibition
Tuesday, January 28, 2020
4:00 – 4:30 p.m. PST
San Diego Convention Center
- (1216-B) A Novel Objective Waveform Analysis for Providing Bias-free Multiparametric Outputs for Classifying Biological Mechanisms and High-Throughput Screening Results
- (1131-B) Assessment of Compound Efficacy and Safety for Glioblastoma Treatment in Multiplexed Human High Throughput Screening Platform
- (1077-C) Complex Event Analysis for Neurotoxic Profiling of Compound Effects on Human iPSC-Derived Neural Spheroid 3D Cultures
- (1137-C) High Throughput Profiling of Cardio-Active Compound Response Between 2D Monolayers, Anisotropic and 3-Dimensional Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
- (1128-D) A Human Pancreatic Spheroid Platform for High Throughput Screening in Toxicology and Diabetes
- (1134-E) Anisotropic High Throughput Human iPSC-Derived Cardiomyocyte Cultures Display Differential Response to Chronic Oncology Compound-Related Toxicity
StemoniX is accelerating the discovery of new medicines to treat challenging diseases via the world's first ready-to-use assay plates containing living human microOrgans®, including electrophysiologically active neural (microBrain®) and cardiac (microHeart®) cells. Predictive, accurate, and consistent, StemoniX's products combined with its proprietary data management and analytical tools (AnalytiX™) are revolutionizing traditional drug discovery and development by radically improving the speed, accuracy and costs required to identify new drugs and conduct initial human cell toxicity and efficacy testing. Through its Discovery as a Service offering, the company partners with organizations to screen compounds as well as to create customized microOrgan models and assays tailored to specific discovery and toxicity needs. Visit www.stemonix.com to learn how StemoniX is helping global institutions humanize drug discovery and development to bring the most promising medicines to patients.
Maureen McEnroe, CFA
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