Block & Pfizer Develop Pharma Manufacturing System
Block Engineering and Pfizer have joined forces to develop a new light-based system for use in pharmaceutical manufacturing.
Block Engineering; known for its specialism in quantum cascade laser spectroscopy has signed an agreement with the Viagra maker to design a real-time, non-contact system for cleaning verification of vessels used in the production process. The technology is based on Block's commercially available “LaserScan” analyser.
According to Block and Pfizer, accurate cleaning verification of those vessels has a significant impact in pharmaceuticals manufacturing, because of the potential health risks of cross-contamination between products.
Currently, to ensure that the walls of the vessels meet stringent US FDA cleanliness standards, swabs are applied to collect samples for off-line analysis. The swabs are then analysed, typically with wet chemistry instruments like high-pressure liquid chromatography (HPLC) systems.
Those measurements can take several hours or more per vessel, during which time it usually remains idle, creating a production bottleneck. “The key value proposition of the proposed technology is to eliminate this bottleneck and provide a handheld, battery-operated, barcode-scanner-like device capable of providing real-time, noncontact verification of the cleanliness of the vessel walls,” say Block and Pfizer.
Using QCL spectroscopy should mean that the manufacturing equipment could be scanned for contamination in just minutes, identifying any areas that require additional cleaning without any need for sampling with swabs.
“Cleaning verification is a critical step in the drug manufacturing process and Pfizer is committed to the development of technologies that could decrease inspection times, reduce costs and improve supply assurance,” said Steve Hammond, Head of Pfizer’s Process Analytical Sciences Group (PASG).
Five minutes with Stanley Healthcare's Troy Dayon
Stanley Healthcare provides technology solutions for caregivers, whether they are in a hospital, a care home, or at home. Here the company's President Troy Dayon explains the challenges carers face and what role technology plays in care for the elderly.
The healthcare workforce is shrinking while the population is aging. How can this be addressed?
Not only is the healthcare workforce shrinking, but the industry is facing the issue of overload and burnout among healthcare professionals.
One major approach to address this is to help each caregiver to accomplish more – not by pushing them harder but by focusing their attention on the things that matter most, harnessing technology such as AI and machine learning.
This technology provides caregivers with information on what care is needed, and which patients or residents to focus on first based on risk or acuity. The insights that it provides can help caregivers to be more efficient and address issues that would usually require more of their time, such as critical asset location, which takes time away from giving the care where it’s needed most.
What do healthcare providers need to do to address clinician burnout?
It is key for healthcare providers to understand the setting and the specific environment in which clinicians have been working. Many hospitals across the globe reconfigured entire wards to treat COVID-19 patients, and for more than a year, clinicians have been working in crisis mode.
They need the opportunity to return to regular, sustainable routines, supported by technologies that help make them more efficient, but also more fulfilled because they maximise time with patients, applying their hard-earned education and experience to work at the top of their license.
In aged care, the experience of managing a highly contagious and deadly virus has reinforced the need for a proactive approach to managing the health of residents. Caregivers need predictive tools like the Foresite solution to help them understand which residents are at greatest risk, so they can focus their efforts where they can have the most impact.
How can technology support older people?
AI-based technology such as Foresite harnesses a range of passive monitoring technologies to develop a baseline profile of a resident in aged care that highlights changes in health or behaviour. This information can help caregivers see where and when they need to spend their time, identifying heightened risk for falls and early indication of heart issues and even infections.
In fact, the technology has been shown to accurately predict events like falls, which allows intervention prior to an event occurring, rather than just automating routine processes.
Beyond this, connecting caregivers remotely to seniors to provide efficient care outside of traditional care settings is crucial. During the pandemic, there was a marked increase in the use of telehealth and remote monitoring of vitals, medication management and daily health.
These technologies fill a major gap in healthcare delivery: care for patients once they’ve been discharged from hospital, or for seniors who need some level of care but don’t need to be in an aged care home. By caring for people effectively in their own homes, we can help reduce the burden on hospitals from readmissions and leverage the expertise of aged care organisations beyond the confines of the four walls of the facility.
A lot of care is in fact delivered by unpaid carers. How can they be better supported with tech?
The remote monitoring technology that professional caregivers have access to can, in turn, also provide information and support to unpaid caregivers. For example, helping ensure a loved one is taking their medication, or knowing when they might be experiencing a change in health that can put them at risk.
Human observation is inherently limited, no matter how often you see a loved one, and you can’t always rely on what a senior says about themselves. It’s very common that they downplay problems, because no one wants to be a burden or relinquish their independence.
Remote solutions that connect family to an older relative help increase safety and wellbeing for the senior and reduce the burden on caregivers. They also make possible care decisions based on facts. At some point, a senior may need to transition to an aged care setting, which is often a difficult family conversation. This is an area where we can offer support to unpaid caregivers – reassurance during what is typically a very stressful period for the people providing that care.
In Japan several large hospitals are deploying robot nurses. Is this a potential solution?
I think the best path for robotics in healthcare is to focus on the root problem. It’s about dealing with a limited number of caregivers for a population that’s rapidly aging. Robotic technologies offer solutions that support the human healthcare providers with the information they need to make better and faster decisions about care. It’s about convergence and use of technology rather than a specific solution such as a robotic nurse.
This technology could be in the form of AI and machine learning or a robotic agent for routine administrative tasks. Removing low-value activities that distract caregivers from giving care is a key focus when it comes to robotics in healthcare. This automation can free up time for caregivers to spend more time with patients while optimising workflows.
Robots in this sense don’t replace humans. They are leveraged for what they do well – repetitive routines done with speed and precision – while humans are given the time and space to deliver what ultimately we all want: human-centered care.