May 17, 2020

INTRODUCING: The LifeFlow Left Ventricular Assist Device

LifeFlow Left Ventricular Assist Device
long term treatment
3 min
The LVAD is designed to treat heart-failure long term
Healthcare Global talks to Professor John Knight about a prototype artificial heart pump designed for the long-term treatment of heart failure. John ta...

Healthcare Global talks to Professor John Knight about a prototype artificial heart pump designed for the long-term treatment of heart failure. John talks about how this life-changing technology has been developed and how software reliability is achieved using ‘SPARK’, AdaCore’s toolkit for the Ada programming language. John envisions a medical future where computers will increasingly play a role in safeguarding the lives of patients in our hospitals.

HCG: What is the LifeFlow Left Ventricular Assist Device (LVAD) and how does it work?

JK: An LVAD is a device that supplements the pumping capability of the left ventricle for patients with insufficient natural pumping capacity. Heart failure occurs when the heart loses its ability to pump enough blood through the body. With the LifeFlow, a patient’s heart pumping can be supplemented synthetically. Magnetic bearings suspend a rotating entity such as the impeller in the LifeFlow in a magnetic field, thereby eliminating the need for mechanical support. These bearings allow a pump to be built without mechanical contact between the impeller and the casing. This helps to reduce damage to blood cells.

What are the benefits of the device to patients?

There are many benefits, but an important one is the prospect for reducing blood-cell damage.

How is reliability maintained so that patients can trust the technology and be sure that their wellbeing is being safeguarded?

The software in medical devices has a very high cost of failure (the patient might be injured), and so ultra-high levels of dependability are required. In complex devices such as the LifeFlow, some of the computations have to be carried out in real time. Assurance is best obtained by appealing to formal (mathematical) languages and mathematical proofs. The statement of what the software has to do in the LifeFlow, called the specification, was prepared in a mathematical language and many of the properties of the software were checked using an automatic theorem prover.

Tell me more about the 'Echo process' and how doctors can put their trust in software written by computers.

Echo is a new software technology developed at the University of Virginia. The proof for LifeFlow was actually created by computers, not humans, and the entire Echo approach relies heavily on the existing capabilities of SPARK Ada and its associated tools. 

Are there any plans for the 'LifeFlow' prototype to be implemented in hospitals?

The current state of the project is that it remains at the early prototype stage and is ‘on hold’ because no manufacturer has been identified who can fabricate the intricate form of the impeller and casing.

Do you envisage similar devices being key players in the future of healthcare technology?

Devices that include powerful computers and innovative software seem very likely to contribute to the future of healthcare technology. As can be seen in the current generation of devices, computers bring new opportunities for functionality for healthcare systems.

What technology do you think will lead the way in terms of healthcare innovation in the next decade?

The future of healthcare innovation will certainly include software-intensive digital systems. Technology that provides the necessary software productivity and dependability will very likely be a major player in healthcare innovation.

John Knight is a professor of computer science at the University of Virginia. He holds a B.Sc. (Hons) in Mathematics from the Imperial College of Science and Technology (London) and a Ph.D. in Computer Science from the University of Newcastle upon Tyne. Prior to joining the University of Virginia in 1981, he was with NASA's Langley Research Centre.

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Jun 18, 2021

Skin Analytics wins NHSX award for AI skin cancer tool 

2 min
Skin Analytics uses AI to detect skin cancer and will be deployed across the NHS to ease patient backlogs

An artificial intelligence-driven tool that identifies skin cancers has received an award from NHSX, the NHS England and Department of Health and Social Care's initiative to bring technology into the UK's national health system. 

NHSX has granted the Artificial Intelligence in Health and Care Award to DERM, an AI solution that can identify 11 types of skin lesion. 

Developed by Skin Analytics, DERM analyses images of skin lesions using algorithms. Within primary care, Skin Analytics will be used as an additional tool to help doctors with their decision making. 

In secondary care, it enables AI telehealth hubs to support dermatologists with triage, directing patients to the right next step. This will help speed up diagnosis, and patients with benign skin lesions can be identified earlier, redirecting them away from dermatology departments that are at full capacity due to the COVID-19 backlog. 

Cancer Research has called the impact of the pandemic on cancer services "devastating", with a 42% drop in the number of people starting cancer treatment after screening. 

DERM is already in use at University Hospitals Birmingham and Mid and South Essex Health & Care Partnership, where it has led to a significant reduction in unnecessary referrals to hospital.

Now NHSX have granted it the Phase 4 AI in Health and Care Award, making DERM available to clinicians across the country. Overall this award makes £140 million available over four years to accelerate the use of artificial intelligence technologies which meet the aims of the NHS Long Term Plan.

Dr Lucy Thomas, Consultant Dermatologist at Chelsea & Westminster Hospital, said: “Skin Analytics’ receipt of this award is great news for the NHS and dermatology departments. It will allow us to gather real-world data to demonstrate the benefits of AI on patient pathways and workforce challenges. 

"Like many services, dermatology has severe backlogs due to the COVID-19 pandemic. This award couldn't have come at a better time to aid recovery and give us more time with the patients most in need of our help.”

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