Jul 6, 2018

Top 10 innovative healthcare pioneers

Top 10
healthcare services
Genetics
Cancer
Catherine Sturman
5 min
The World Economic Forum has released its top Technol...

The World Economic Forum has released its top Technology Pioneers. We take a look at the top 10 which made the list.

  1. Applied Brain Research Inc

An AI company in the field of neuromorphic artificial intelligence interactive development, Applied Brain Research has sought to utilise artificial neurons which compute like a brain. The process has guaranteed a reduction in power, as well as increased responsivity and precision.

It software tool, Nengo, has been used to create its 2.5mn neuron brain model, named Spaun. The model has been described as “smarter than monkeys when it comes to recognising syntactic patterns, structured patterns in the input, that monkeys won't recognise.”

  1. BenevolentAI

With a growing interest in the AI pharmaceutical sector, UK company BenevolentAI has recently been valued at over $2bn following its latest $115mn funding round.

Utilising AI as a way of discovering new medicines and treatments for complex diseases, such as Parkinson’s, its drug development portfolio has proven that it can cut drug discovery by up to four years and deliver increased efficiencies of 60% in the development process, compared to the averages displayed in the pharma industry.

For an industry that spends $180bn on research and development annually, its technology offers significant potential.

  1. Seismic

Integrating apparel with robotics, Seismic has developed ‘Powered Clothing’ to help users maintain their movement. Its flex drives house electric motors that act like additional muscles to support those with limited mobility.

Sensors also work to help track the movement to assist users and learn more about how it can provide further support.

With a global ageing population, Seismic encompasses wellness products, as well as medical and industrial applications, with the aim to support those to maintain independence, dignity and confidence.

  1. Soft Robotics

Soft Robotics strives to develop automation solutions and soft robotic gripping systems that can grasp and manipulate items.

Encompassing human hand-like dexterity, its technologies can be used in packing applications, and can support pharmaceutical manufacturing, handling small, defined objects with minimal impact.

  1. Vayyar

Winning a number of awards, Israeli based Vayyar has developed a sophisticated, low-cost imaging sensor, which will become invaluable in the medical sector.

Tracking all information in real-time, its sensor can monitor vital signs and identify obstacles. With the ability to penetrate through materials, such as plastic, it can be safety used in early stage breast cancer detection, providing a 3D scan of breast tissue that identifies tumours in under five seconds.

  1. 1928 Diagnostics

Gothenburg-based Swedish company 1928 Diagnostics works to fight antibiotic resistance through its automated platform to analyse the genetic code of bacteria.

By analysing raw data from whole genome sequencing (WGS) machines, the company matches the data to proprietary databases through the use of cloud web services.

Results surrounding the form of resistance and typing profile is delivered to clients are provided in minutes, providing exceptional support within antibiotic treatment for infected patients.

The results also include virulence factor detection and epidemiologic typing.

“The recent award encourages the 1928 Diagnostics team to work even harder to erase and/or bridge the gap between DNA technology and infection control, an effort that will ultimately save many lives,” said CEO Kristina Lagerstedt.

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“At the same time, we want to use this opportunity to leverage the importance of global collaboration to save the power of antibiotics and fight antibiotic resistant bacteria – one of the greatest threats against humanity.”

  1. Color Genomics

Featured in the February edition of Healthcare Global, Color Genomics is helping to solve one of the world's biggest healthcare problems: cancer, combining state-of-the-art technology and genetics.

Prevention and early detection could create huge savings for healthcare services around the world, as well as the clear benefits to people's lives.

"There is no incentive for people to not get genetic counselling," explained Othman Laraki, Co-founder and CEO of Color.

Color’s tests currently analyse 30 different genes associated with eight common types of hereditary cancer as well as cardiovascular risk. Patients order the testing kits online, provide a blood or saliva sample, and within a couple of weeks the results are emailed back to both them and their doctors.

After this, they can discuss the results with Color's genetic counsellors and move on to the next steps. With all the initial consultations done online, this is a low overhead process saving doctors valuable time.

The technology is extremely precise and is being used in clinical labs around the world, including the UK’s NHS. When a gene mutation is found it is sequenced for a second time to ensure accuracy. "We've literally never had one where the first one proved to be wrong," Laraki adds.

Color constantly updates its model when new genes are discovered, and when there is a medical consensus to confirm these can lead to serious health problems. Recently it launched Color Prime for people to keep up to date with these latest discoveries.

  1. Narrative Science (data)

Located in Chicago, Narrative Science has developed Quill, which helps businesses analyse and interpret data to provide actionable insights. Underpinned by Natural Language Generation (NLG), its narrative guarantees enhanced decision making, empowering employees and improving the customer experience.

  1. uBiome

Similar to Color Genomics, uBiome provides home-testing kits in its bid to support customers in the analysis of their microbiome and take greater control of their health.

Providing tests to look ways to manage gut conditions, such as Irritable Bowel Syndrome and Crohn’s Disease (through SmartGut), STIs and HPV (through its SmartJane test) and track diet and lifestyle choices (through Explorer), the wellness company utilises machine learning, artificial intelligence, advanced statistical techniques, as well as precision sequencing. Customers can collect their sample in under two minutes, where results are able to be downloaded.

  1. Modern Meadow (animal free leather)

Harnessing biofabrication, Modern Meadow has developed the first bioleather materials made without animals, where waste has also been reduced by up to 80% in the process.

Optimising collagen production, the company has created a bioleather material, Zoa, which can be created into any form and combine seamlessly with any other material.

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Dec 10, 2018

Top 10 healthcare innovations for 2019

Telemedicine
medical devices
Top 10
Genetics
Catherine Sturman
6 min
healthcare innovations
We take a look at some of the top 10 healthcare innovations which are transforming the sector

We take a look at some of the top 10 healthcare innovations which are transforming the sector

10. Telehealth

The telehealth market is booming. Consumers are leading increasingly busy lifestyles, with up to 60% favouring digitally-led services. Providing clinical care at a distance, increasing accessibility and eradicating potential delays has given patients greater control, boosting patient satisfaction and overall engagement. Such is its exponential growth, The Centers for Medicare and Medicaid Services in the US has recently released its proposed Physician Fee Schedule and Qualified Payment Programme updates for 2019, where telehealth services has been heavily featured, in order to deliver ‘different access points’ for patients.  

9. Mobile technology

Consumers have become accustomed to accessing their data through the use of various digital tools, where the use of mobile and tablet health apps has tripled from 13% in 2014 to 48% today. Catering to this growing market, British based start-up Babylon Health is making waves on a global scale. Partnering with the National Health Service (NHS) and private health provider, Bupa, it has also cemented its presence across the flourishing Chinese market, with a membership base exceeding 1.4mn citizens across Europe, Asia and Africa. By partnering with global juggernaut Tencent, Babylon’s artificial intelligence system has enabled both parties to interact directly with users, identify specific illnesses, deliver health status assessments, and triage necessary actions. The mobile app is available to over a billion users and linked to more than 38,000 medical facilities in China alone.

8. Artificial intelligence 

Artificial intelligence (AI) applications, such as predictive analytics for patient monitoring has provided significant financial savings. Applications that target hospitals and medical institutions include patient monitoring and transcribing notes for electronic health records (EHRs). The European Union is set to invest $24bn into artificial intelligence (AI) by 2020 in a bid to catch up with Asia and the US, who have invested heavily in AI and cloud services. This year, Google revealed its plans to harness AI and machine learning across a multitude of consumer technologies, particularly in healthcare. “If AI can shape healthcare, it has to work through the regulations of healthcare. In fact, I see that as one of the biggest areas where the benefits will play out for the next 10-20 years,” Google CEO Sundar Pichai has previously stated.

7. Blockchain

Blockchain is estimated to reach over $5.61bn by the end of 2025, even though it remains dependent on the ability to record and store information conveniently, economically and securely amongst different applications and systems. Providing transparency and eliminating third-party intermediaries, processes are streamlined, reducing healthcare costs exponentially. Unlocking the ability for providers to deliver a value-based healthcare system and enhance patient engagement, blockchain could save the industry up to $100-$150bn per year by 2025 in data breach-related costs, IT costs, operations costs, support function costs and personnel costs, according to BIS Research. Partnering with pharmaceutical giant GlaxoSmithKline (GSK), Ethereum blockchain-based supply chain platform, Viant sought to accelerate the pace of blockchain-based supply chain systems. Accenture and supply chain giant DHL have also developed a blockchain-based serialisation prototype which tracks pharmaceuticals from the point of origin to the consumer.

6. Health wearables

With the rise of lifestyle diseases, such as diabetes, more consumers are turning to health wearables that monitor glucose, heart rate, physical activity and sleep to gain a greater understanding of their health conditions. Following on from the release of the first Bluetooth headset back in 2000, the growing interest in wearables has seen monitoring our health and data become standardised. This data can be analysed by sophisticated algorithms to drive long-term diagnosis and support. Partnering with Google, health wearables company Fitbit is exploring the development of consumer and enterprise health solutions. Its acquisition of HIPAA-compliant health platform, Twine Health has seen the business enhance its clinical services by bringing on board a coaching platform, empowering people to seek better health outcomes.

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5. Electronic health records tools

From 2018-2022, the electronic health records (EHR) market is expected to grow at a compound average rate of 6% per year Providers and organisations continue to house fragmented technologies which create barriers towards collaboration and data sharing opportunities. This is further exacerbated if a patient straddles both public and private healthcare. Technology giant Apple has integrated patients’ medical records into its Health App as part of its iOS 11.3 beta. The data is encrypted and protected with the user’s iPhone passcode. Partnering with hospital providers and clinics, patients are now able to view their medical records from multiple providers within one platform. Johns Hopkins Medicine, Cedars-Sinai, Penn Medicine, UC San Diego Health and even the Cleveland Clinic have implemented this technology.

4. Healthcare transportation 

Non-emergency health transportation remains a key issue worldwide, preventing patients from getting to or from a doctor’s appointment. 25% of lower-income patients have missed or rescheduled appointments due to lack of transportation, costing US health systems up to $150bn each year. Transportation companies such as Lyft and Uber have therefore entered the market by partnering with state governments to reduce these costs and deliver personalised patient care.

3. 3D Printing 

Healthcare providers are set to represent the second largest industry sector in 3D manufacturing. The Food & Drug Administration’s decision to release its first comprehensive framework advising manufacturers of 3D medical products highlights its growing impact where more than 100,000 knee replacement surgeries are completed each year using 3D-printed, patient-matched surgical guides, for example. Through this process, surfaces and structures can be optimised for strength, weight and material use. Consultation between surgeons and patients has also been bolstered, where patients can better understand the complexity of his or her specific needs.

2. Genomics

As consumers get more involved in the management of their health, consumer genetics and research companies have grown in popularity and scale. People want to further understand their genetic makeup, leading personal genomics and biotech company 23andMe to become one of the largest consumer-based organisations worldwide. Interestingly, this year, the company has entered a four-year collaboration with GSK to develop new treatments, but using human genetics as the basis for discovery.

Not only looking to develop treatments by analysing human genetics, pharmaceutical companies are looking to even remove hereditary genes which pass diseases down generations. In 2017, human embryos were successfully ‘edited’ through gene editing tool, CRISPR (Clustered, Regularly Interspaced, Short Palindromic Repeats), eradicating hypertrophic cardiomyopathy within 42 embryos.

1. Vertical integrations

As healthcare providers aim to provide greater transparency, promote collaboration and lower escalating patient costs, 2018 has been the year for a significant number of vertical integrations. CVS Health’s $68mn takeover of health insurer Aetna is a case in point. By influencing more of the supply chain, it will gain significant negotiating power to reduce costs for payers and patients, develop personalised solutions and improve overall outcomes. It will also promote the eradication of delays in process by removing any third parties within traditional business models. Other notable integrations are Optum’s acquisition of the DaVita Medical GroupHumana and Kindred Healthcare and Cigna and Express Scripts.

Reports have indicated that not only has the number of healthcare deals more than doubled in the last five years, the size of deals has also grown as a result of repeat investor interest, highlighting that this trend is here to stay.

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